1: 1.) NaNO2, conc. HCl; 2.) CuCl2*2H2O / 1.) water, 0.5 h, 0 to 5 deg C; 2.) acetone, 0 deg C 2: NH2OH*HCl, NaOAc / ethanol; H2O / 3.5 h / Heating 3: Ac2O / 2.5 h / Heating View Scheme

1: NH2OH*HCl, NaOAc / ethanol; H2O / 3.5 h / Heating 2: Ac2O / 2.5 h / Heating View Scheme

1: 1.) NaNO2, conc. HCl; 2.) CuCl2*2H2O / 1.) water, 0.5 h, 0 to 5 deg C; 2.) acetone, 0 deg C 2: NH2OH*HCl, NaOAc / ethanol; H2O / 3.5 h / Heating 3: Ac2O / 2.5 h / Heating View Scheme

acetic anhydride 2.5 h; Heating;