2-氯-N,N-二甲基烟酰胺合成路线 （共 5 条）
反应条件
1: (COCl)2, DMF / CH2Cl2 / 4 h / Heating 2: tetrahydrofuran; H2O / 3 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 17 p. 2674 - 2687
参考文献
Mikata, Yuji; Maesaki, Ryoko
Acta Crystallographica Section C: Crystal Structure Communications, 1999 , vol. 55, # 6 p. 973 - 975
反应条件
thionyl chloride 1) r.t., 48 h, then reflux for 8 h, 2) CHCl3, 0 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 9 p. 2178 - 2199
反应条件
in N-methyl-acetamide; water
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4789393 A1, 1988 ;
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II)
different alkylmagnesium chlorides; Product distribution;
参考文献
Mikata, Yuji; Maesaki, Ryoko
Acta Crystallographica Section C: Crystal Structure Communications, 1999 , vol. 55, # 6 p. 973 - 975
