反应条件
1: 94 percent / p-TsOH / benzene / 13 h / Heating 2: 98 percent / imidazole / dimethylformamide / Ambient temperature 3: 1.) LDA, potassium 1,1-dimethylpropoxide, 2.) B(OMe)3, 3.) 30percent aq. H2O2 4: 1.) (PhO)3PCH3I, 2.) Bu4NF / 1.) DMF, RT, 24 h, 2.) THF, RT, 4 h 5: 98 percent / aq. HCl / methanol / 2 h / Ambient temperature View Scheme
参考文献
Rao, Pemmaraju N.; Wang, Zhiqiang
Steroids, 1997 , vol. 62, # 6 p. 487 - 490
