4-氟-4’-甲基二苯甲酮合成路线 （共 23 条）
反应条件
1,10-phenanthroline; palladium(II) oxide hydrate; trifluoroacetic acid in 1,4-dioxane; water T=110°C; 20 h; AirClosed vessel;
参考文献
Liu, Jing; Zhou, Xianya; Rao, Honghua; Xiao, Fuhong; Li, Chao-Jun; Deng, Guo-Jun
Chemistry - A European Journal, 2011 , vol. 17, # 29 p. 7996 - 7999
反应条件
1: p-fluorobenzenesulfonyl chloride With sodium hydrogencarbonate; sodium sulfite AirHeating; 2: 4-cyanotoluene With 1,10-phenanthroline; palladium(II) oxide hydrate; trifluoroacetic acid in 1,4-dioxane; water T=110°C; 20 h; AirClosed vessel;
参考文献
Liu, Jing; Zhou, Xianya; Rao, Honghua; Xiao, Fuhong; Li, Chao-Jun; Deng, Guo-Jun
Chemistry - A European Journal, 2011 , vol. 17, # 29 p. 7996 - 7999
反应条件
triethylamine; pyridinium chlorochromate in dichloromethane T=20°C;
参考文献
Organic Letters, , vol. 14, # 18 p. 4850 - 4853,4
反应条件
1.1: magnesium / tetrahydrofuran / 2 h / 20 - 85 °C 1.2: 0 - 20 °C / |Inert atmosphere 2.1: pyridinium chlorochromate; triethylamine / dichloromethane / 20 °C View Scheme
参考文献
Organic Letters, , vol. 14, # 18 p. 4850 - 4853,4
反应条件
1.1: magnesium / tetrahydrofuran / 2 h / 20 - 85 °C 1.2: 0 - 20 °C / |Inert atmosphere 2.1: pyridinium chlorochromate; triethylamine / dichloromethane / 20 °C View Scheme
参考文献
Organic Letters, , vol. 14, # 18 p. 4850 - 4853,4
反应条件
aluminium trichloride
参考文献
Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, , vol. 7, p. 803,805
参考文献
Conte, L.; Napoli, M.; Gambaretto, J. P.; Guerrato, A.; Carlini, F. M.
Journal of Fluorine Chemistry, 1994 , vol. 67, # 1 p. 41 - 46
反应条件
1: SOCl2 2: AlCl3 / chlorobenzene View Scheme
参考文献
Bulletin des Societes Chimiques Belges, , vol. 75, p. 199 - 229
反应条件
sulfuric acid; dihydrogen peroxide; acetic anhydride; acetic acid 1.) r.t., 4 h; Yield given. Multistep reaction;
参考文献
Conte, L.; Napoli, M.; Gambaretto, J. P.; Guerrato, A.; Carlini, F. M.
Journal of Fluorine Chemistry, 1994 , vol. 67, # 1 p. 41 - 46
反应条件
sulfuric acid; dihydrogen peroxide; acetic anhydride; acetic acid 1.) r.t., 4 h; Yield given. Multistep reaction;
参考文献
Conte, L.; Napoli, M.; Gambaretto, J. P.; Guerrato, A.; Carlini, F. M.
Journal of Fluorine Chemistry, 1994 , vol. 67, # 1 p. 41 - 46
