反应条件
1: tetrahydrofuran / -78 °C 2: 1.) O3, 2.) NaBH4 / 1.) CH2Cl2, -78 deg C 3: Et3N / 0 °C 4: 1N-HCl / tetrahydrofuran / Ambient temperature 5: K2CO3 / methanol 6: NaH / tetrahydrofuran / Ambient temperature 7: camphorsulfonic acid / CH2Cl2 / 0 °C 8: DMSO, (COCl)2, Et3N / CH2Cl2 9: 28 percent / (Ph3P)3RhCl / acetonitrile / 160 °C 10: DDQ / CH2Cl2; H2O 11: DMSO, (COCl)2 / CH2Cl2 12: TsOH / benzene 13: H2 / Pd-C / ethyl acetate 14: CrO3, H2SO4 / acetone 15: 2N-HCl / tetrahydrofuran / Ambient temperature 16: (C6H11)2NMgBr / methanol / -55 °C 17: DDQ / CH2Cl2 / 1.5 h / Ambient temperature; buffer (pH 6.86) View Scheme
参考文献
Tetrahedron Letters, , vol. 29, # 40 p. 5143 - 5146
