2-甲氧基-6-甲基苯甲腈合成路线 (共 15 条)
参考文献
Gibson
Journal of the Chemical Society, 1923 , vol. 123, p. 1272
反应条件
1: alcoholic NaOH-solution 2: nitrous acid View Scheme
参考文献
Gibson
Journal of the Chemical Society, 1923 , vol. 123, p. 1272
反应条件
1: alcoholic NaOH-solution 2: nitrous acid 3: permanganate; natrium carbonate View Scheme
参考文献
Gibson
Journal of the Chemical Society, 1923 , vol. 123, p. 1272
反应条件
1: in tetrahydrofuran
6 h; Reflux;
2: With hydrogenchloride in water
T=75°C; 20 h;
参考文献
Bryan, Marian C.; Biswas, Kaustav; Peterkin, Tanya A.N.; Rzasa, Robert M.; Arik, Leyla; Lehto, Sonya G.; Sun, Hong; Hsieh, Feng-Yin; Xu, Cen; Fremeau, Robert T.; Allen, Jennifer R.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 619 - 622
反应条件
1.1: tetrahydrofuran / 6 h / Reflux
1.2: 20 h / 75 °C
2.1: boron tribromide / dichloromethane / 1 h / -78 - 23 °C
View Scheme
参考文献
Bryan, Marian C.; Biswas, Kaustav; Peterkin, Tanya A.N.; Rzasa, Robert M.; Arik, Leyla; Lehto, Sonya G.; Sun, Hong; Hsieh, Feng-Yin; Xu, Cen; Fremeau, Robert T.; Allen, Jennifer R.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 619 - 622