palladium diacetate; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=40°C; 1 h; Inert atmosphere;

1: 1-bromo-4-methoxy-benzene; bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methane With Pd0(tris(tert-butyl)phosphine)2; potassium hydroxide in 1,4-dioxane; water T=20°C; Suzuki-Miyaura Coupling; 3 h; Inert atmosphere; 2: 1-bromo-3-methyl-benzene With potassium hydroxide in 1,4-dioxane; water T=60°C; Suzuki-Miyaura Coupling; 16 h; Inert atmosphere;

anhydrous nickel; carbon in tetrahydrofuran Kumada reaction; 0.166667 h; Heating;

1: p-toluenesulfonic acid / benzene / Heating 2: CF3SO3H / 7 h / 110 °C View Scheme

trifluorormethanesulfonic acid T=110°C; 7 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

scandium tris(trifluoromethanesulfonate); Trimethylene glycol T=125°C; 16 h; Yield given. Yields of byproduct given;