4’-甲氧基-3-硝基-1,1’-联苯合成路线 （共 28 条）
反应条件
copper bronze
T=225 - 235°C;
参考文献
Kreiter et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 5770,5772
反应条件
[2,2']bipyridinyl; palladium (II) trifluoroacetate in nitromethane
T=110°C; 48 h; Inert atmosphere;
参考文献
Qian, Cheng; Chen, Jiayan; Fu, Meiqin; Zhu, Shiya; Chen, Wen-Hua; Jiang, Huanfeng; Zeng, Wei
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 36 p. 6013 - 6022
反应条件
1.1: 73 percent / diethyl ether / 0 - 20 °C
2.1: TBAF / tetrahydrofuran
2.2: 90 percent / TBAF; (t-Bu)3P / [(allyl)PdCl]2 / tetrahydrofuran / 1 h / Heating
View Scheme
参考文献
Denmark, Scott E.; Wu, Zhicai
Organic Letters, 1999 , vol. 1, # 9 p. 1495 - 1498
反应条件
copper(l) chloride in methanol
T=25°C; 4 h;
参考文献
Cheng, Guanjun; Luo, Meiming
European Journal of Organic Chemistry, 2011 , # 13 p. 2519 - 2523
反应条件
1: sodium sulfate / toluene / 0.5 h / 20 °C
2: [2,2']bipyridinyl; palladium (II) trifluoroacetate / nitromethane / 48 h / 110 °C / |Inert atmosphere
View Scheme
参考文献
Qian, Cheng; Chen, Jiayan; Fu, Meiqin; Zhu, Shiya; Chen, Wen-Hua; Jiang, Huanfeng; Zeng, Wei
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 36 p. 6013 - 6022
反应条件
in various solvent(s)
18 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Effenberger, Franz; Koch, Markus; Streicher, Willi
Chemische Berichte, 1991 , vol. 124, # 1 p. 163 - 173
参考文献
Makarowa et al.
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1958 , p. 1452,1457; engl. Ausg. S. 1399, 1404
反应条件
hydrogen bromide; acetic acid
参考文献
Astra Pharmaeuticals Ltd.
Patent: US5977105 A1, 1999 ;
US 5977105 A
