反应条件
1: 75 percent / bromine / acetic acid / 12 h
2: 2.) SOCl2 / 1) THF, 0 deg C, 30 min; 2) THF, 1 h
3: 1.) n-BuLi / 1) THF, hexane, -78 deg C, 1 h; 2) THF, hexane, -78 deg C --> rt
4: SnCl4 / toluene / 0.33 h / 0 °C
5: 95 percent / H2 / Pd/C / ethyl acetate / 72 h
View Scheme
参考文献
Broering, Teresa J.; Morrow, Gary W.
Synthetic Communications, 1999 , vol. 29, # 7 p. 1135 - 1142
