Tetrahexylammonium bromide in N,N-dimethyl-formamide; toluene 72 h; Ambient temperature;

1: 65 percent / triethylamine / tetraethylammonium bromide / CH2Cl2; dimethylformamide / 48 h / Ambient temperature 2: 60 percent / 1.) potassium tert-butoxyde, 2.) mercury(II) oxide, mercury(II) chloride / dimethylsulfoxide; acetone; H2O / 1.) methyl sulfoxide, potassium tert-butoxide, 100 deg C., 2h, 2.) mercury(II) oxide, mercury(II) chloride, aceton-water, 30 min., room temperature 3: 70 percent / molecular sieve 4 Angstroem, mercury(II) cyanide / benzene; nitromethane / 40 °C 4: hydrogen / 10percent Pd/C / methanol / 36 h / Ambient temperature 5: sodium methoxide / methanol; H2O View Scheme