反应条件
1: N-bromosuccinmide; dibenzoyl peroxide / tetrachloromethane / |Reflux
2: potassium carbonate / N,N-dimethyl-formamide / 5 h / 70 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / 5 h / 0 °C
View Scheme
参考文献
CALITHERA BIOSCIENCES INC.; LI, Jim; CHEN, Lijing; GOYAL, Bindu; LAIDIG, Guy; STANTON, Timothy, Friend; SJOGREN, Eric, Brian
Patent: WO2013/78123 A1, 2013 ;
WO 2013/078123 A1
