2-(2-丙炔基硫代)乙醇合成路线 （共 3 条）
反应条件
1: 2-hydroxyethanethiol With sodium hydride in N,N-dimethyl-formamide; mineral oil
T=0°C;
2: propargyl bromide in N,N-dimethyl-formamide; mineral oil
T=0 - 20°C;
参考文献
N.V. Organon
Patent: US2011/28450 A1, 2011 ;
Location in patent: Page/Page column 25-26 ;
US 20110028450 A1
参考文献
Skattebol,L. et al.
Journal of Organic Chemistry, 1968 , vol. 33, # 2 p. 548 - 552
反应条件
1: 52 percent / PBr3 / pyridine / 2 h / -20 - -10 °C
2: 80 percent / ethanol / 24 h / Heating
3: NaOH, hydroquinone / H2O / 1 h / 80 °C
View Scheme
参考文献
Dupuy, Claude; Surzur, Jean-Marie
Bulletin de la Societe Chimique de France, 1980 , vol. 2, # 7-8 p. 353 - 360
