1: 88 percent 2: 63 percent / M-sulphuric acid / Heating View Scheme

1: 88 percent 2: 93 percent / H2 / palladium on charcoal / ethanol 3: 60 percent / M sulphuric acid / Heating View Scheme

1: LiBH4, N,N'-dibenzoyl-D-cystine / 2-methyl-propan-2-ol; tetrahydrofuran / 5 h / -78 °C 2: 5 percent / HN3, DEAD, PPh3 / benzene / 3 h / 0 deg C to RT View Scheme

1: LiBH4, N,N'-dibenzoyl-D-cystine / 2-methyl-propan-2-ol; tetrahydrofuran / 5 h / -78 °C 2: 80 percent / HN3, DEAD, PPh3 / benzene / 3 h / 0 deg C to RT 3: H2 / Pd-C / methanol / 760 Torr / Ambient temperature 4: tetrahydrofuran / 6 h / Ambient temperature 5: imidazole / CH2Cl2 / 3 h / Ambient temperature 6: CF3COOH / CH2Cl2 / 3 h / 0 °C 7: DCC, HOBT / CH2Cl2 / 6 h / 0 deg C to RT 8: TBS-OTf, 2,6-lutidine / CH2Cl2 / 3 h / Ambient temperature 9: DCC, HOBT / CH2Cl2 / 5 h / -5 - 0 °C 10: HF-pyridine / CH2Cl2 / 4 h / Ambient temperature 11: LiOH / tetrahydrofuran; methanol; H2O / 3 h / Ambient temperature 12: DCC, DMAP, DMAP*TFA / CHCl3 / 16 h / Heating View Scheme

[NH2Me2][{RuCl[(R)-dm-segphos]}2(μ-Cl)3]; hydrogen; ammonium salicylate in ethanol T=90°C; P=22502.3 Torr; 15 h; optical yield given as percent eeenantioselective reaction;

Ru(OAc)2((R)-dm-segphos); hydrogen; PhCO2(-)NH4(+) in ethanol T=90°C; P=22502.3 Torr; enantioselective reaction;

hydrogenchloride in ethanol 72 h;

hydrogenchloride in ethanol 72 h;

1: 24 mg / HCl gas / ethanol / 48 h 2: 16 mg / methanol; diethyl ether 3: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme

1: 60 percent / HCl / ethanol / 72 h 2: 68 mg / pyridine View Scheme