5-氨基-2,2-二甲基-1,3-二恶烷-5-甲醇合成路线 （共 7 条）
反应条件
toluene-4-sulfonic acid; N,N-dimethyl-formamide 12 h; Ambient temperature;
参考文献
Forbes, David C.; Ene, Doina G.; Doyle, Michael P.
Synthesis, 1998 , # 6 p. 879 - 882
反应条件
hydrogen; nickel in ethanol T=85°C; P=72400.7 Torr; 4 h;
参考文献
Majewski, Marek; Gleave, D. Mark; Nowak, Pawel
Canadian Journal of Chemistry, 1995 , vol. 73, # 10 p. 1616 - 1626
反应条件
in ethyl acetate; triethylamine; N,N-dimethyl-formamide
参考文献
Morrison-Iverson, Veronique; Wynn, Duncan George
Patent: US2010/233097 A1, 2010 ;
反应条件
toluene-4-sulfonic acid in acetone T=25°C; 3 h;
参考文献
Halabi; Strumia
Journal of Organic Chemistry, 2000 , vol. 65, # 26 p. 9210 - 9213
反应条件
sodium periodate in phosphate buffer
参考文献
Carman, Raymond M.; Handley, Paul N.
Australian Journal of Chemistry, 2001 , vol. 54, # 12 p. 769 - 776
反应条件
1: 85 percent / NaIO4, KH2PO4 / H2O / 1.) 5 deg C, 1 h, 2.) r.t., 5 h 2: 97 percent / LiAlH4 / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Majewski, Marek; Gleave, D. Mark; Nowak, Pawel
Canadian Journal of Chemistry, 1995 , vol. 73, # 10 p. 1616 - 1626
反应条件
1.1: NaIO4; KH2PO4 / H2O / 9 h / 0 - 20 °C 1.2: 86 percent / Na2S2O3 / H2O / 0.25 h 2.1: 50 percent / tetrahydrofuran; hexane / 2 h / 20 °C 3.1: 47 percent / NMO / OsO4 / acetone; H2O / 5 h / 20 °C 4.1: NaIO4 / H2O / 0.5 h / 0 °C 5.1: 270 mg / NaBH4 / H2O / 0.75 h / 0 °C View Scheme
参考文献
Gonzalez-Garcia, Eva Maria; Grognux, Johann; Wahler, Denis; Reymond, Jean-Louis
Helvetica Chimica Acta, 2003 , vol. 86, # 7 p. 2458 - 2470
