(3Z,13Z)-3,13-十八碳二烯-1-基乙酸酯合成路线 （共 52 条）
反应条件
1: pTsOH / 1.5 h 2: 1.) nBuLi / 1.) ether, HMPT, hexane, -10 deg C, 2.) r.t. 3: pTsOH / methanol / 3.5 h / Heating 4: 1) H2/Lindlar / 2) pyridine View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 61, p. 1073 - 1076
反应条件
1: 53 percent Turnov. / lithium salt of 1,3-diaminopropane, 1,3-diaminopropane / 0.17 h / 0 °C 2: pTsOH / 1.5 h 3: 1.) nBuLi / 1.) ether, HMPT, hexane, -10 deg C, 2.) r.t. 4: pTsOH / methanol / 3.5 h / Heating 5: 1) H2/Lindlar / 2) pyridine View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 61, p. 1073 - 1076
反应条件
1: 1.) nBuLi / 1.) ether, HMPT, hexane, -10 deg C, 2.) r.t. 2: pTsOH / methanol / 3.5 h / Heating 3: 1) H2/Lindlar / 2) pyridine View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 61, p. 1073 - 1076
反应条件
1: 70 percent / 30percent hydrogen peroxide / formic acid / 2 h / 30 °C 2: 60 percent / lead tetraacetate / benzene / 3 h / Ambient temperature 3: NaOEt / toluene / 2 h / 25 °C 4: PBr3 5: 98 percent / acetonitrile / 24 h / Heating 6: NaOEt / tetrahydrofuran / 1 h / 25 °C 7: n-BuLi / toluene / 2 h / 25 °C View Scheme
参考文献
Acta Chimica Hungarica, , vol. 125, # 6 p. 797 - 820
反应条件
1: NaOEt / toluene / 2 h / 25 °C 2: PBr3 3: 98 percent / acetonitrile / 24 h / Heating 4: NaOEt / tetrahydrofuran / 1 h / 25 °C 5: n-BuLi / toluene / 2 h / 25 °C View Scheme
参考文献
Acta Chimica Hungarica, , vol. 125, # 6 p. 797 - 820
反应条件
1: 93 percent / lithium aluminium hydride / tetrahydrofuran / 2 h / Heating 2: 70 percent / 30percent hydrogen peroxide / formic acid / 2 h / 30 °C 3: 60 percent / lead tetraacetate / benzene / 3 h / Ambient temperature 4: NaOEt / toluene / 2 h / 25 °C 5: PBr3 6: 98 percent / acetonitrile / 24 h / Heating 7: NaOEt / tetrahydrofuran / 1 h / 25 °C 8: n-BuLi / toluene / 2 h / 25 °C View Scheme
参考文献
Acta Chimica Hungarica, , vol. 125, # 6 p. 797 - 820
反应条件
1: 60 percent / lead tetraacetate / benzene / 3 h / Ambient temperature 2: NaOEt / toluene / 2 h / 25 °C 3: PBr3 4: 98 percent / acetonitrile / 24 h / Heating 5: NaOEt / tetrahydrofuran / 1 h / 25 °C 6: n-BuLi / toluene / 2 h / 25 °C View Scheme
参考文献
Acta Chimica Hungarica, , vol. 125, # 6 p. 797 - 820
反应条件
1: NaOEt / tetrahydrofuran / 1 h / 25 °C 2: n-BuLi / toluene / 2 h / 25 °C View Scheme
参考文献
Acta Chimica Hungarica, , vol. 125, # 6 p. 797 - 820
反应条件
in pyridine; diethyl ether T=25°C; 5 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Synthetic Communications, , vol. 15, # 14 p. 1257 - 1270
反应条件
Lindlar's catalyst; hydrogen 2) pyridine; Multistep reaction;
参考文献
Canadian Journal of Chemistry, , vol. 61, p. 1073 - 1076
