6-溴-7-羟基-2,2-二甲基-苯并[1,3]二恶英-4-酮合成路线 （共 4 条）
反应条件
trifluoroacetic anhydride in trifluoroacetic acid
T=0 - 25°C; 10 h;
参考文献
Tisdale, Eric J.; Vong, Binh G.; Li, Hongmei; Kim, Sun Hee; Chowdhury, Chinmay; Theodorakis, Emmanuel A.
Tetrahedron, 2003 , vol. 59, # 35 p. 6873 - 6887
反应条件
1: 91 percent / Br2 / acetic acid / 4 h / 25 °C
2: 61 percent / TFA; TFAA / 10 h / 0 - 25 °C
View Scheme
参考文献
Tisdale, Eric J.; Vong, Binh G.; Li, Hongmei; Kim, Sun Hee; Chowdhury, Chinmay; Theodorakis, Emmanuel A.
Tetrahedron, 2003 , vol. 59, # 35 p. 6873 - 6887
反应条件
1: With copper(l) iodide; potassium carbonate; potassium iodide in acetone
1 h; Heating;
2: in N,N-dimethyl-formamide; acetone
T=150°C; 15 h;
参考文献
Tisdale, Eric J.; Vong, Binh G.; Li, Hongmei; Kim, Sun Hee; Chowdhury, Chinmay; Theodorakis, Emmanuel A.
Tetrahedron, 2003 , vol. 59, # 35 p. 6873 - 6887
反应条件
1: K2CO3; CuI; KI / acetone / 0.5 h / Heating
2: dimethylformamide / 10 h / 140 °C
View Scheme
参考文献
Tisdale, Eric J.; Li, Hongmei; Vong, Binh G.; Kim, Sun Hee; Theodorakis, Emmanuel A.
Organic Letters, 2003 , vol. 5, # 9 p. 1491 - 1494
