10-溴-2,2,6,6-四甲基-2H-1,5,7-三氧杂-菲-8-酮合成路线 （共 5 条）
反应条件
1: With copper(l) iodide; potassium carbonate; potassium iodide in acetone
1 h; Heating;
2: in N,N-dimethyl-formamide; acetone
T=150°C; 15 h;
参考文献
Tisdale, Eric J.; Vong, Binh G.; Li, Hongmei; Kim, Sun Hee; Chowdhury, Chinmay; Theodorakis, Emmanuel A.
Tetrahedron, 2003 , vol. 59, # 35 p. 6873 - 6887
反应条件
1.1: 91 percent / Br2 / acetic acid / 4 h / 25 °C
2.1: 61 percent / TFA; TFAA / 10 h / 0 - 25 °C
3.1: K2CO3; KI; CuI / acetone / 1 h / Heating
3.2: 90 percent / acetone; dimethylformamide / 15 h / 150 °C
View Scheme
参考文献
Tisdale, Eric J.; Vong, Binh G.; Li, Hongmei; Kim, Sun Hee; Chowdhury, Chinmay; Theodorakis, Emmanuel A.
Tetrahedron, 2003 , vol. 59, # 35 p. 6873 - 6887
反应条件
1.1: 61 percent / TFA; TFAA / 10 h / 0 - 25 °C
2.1: K2CO3; KI; CuI / acetone / 1 h / Heating
2.2: 90 percent / acetone; dimethylformamide / 15 h / 150 °C
View Scheme
参考文献
Tisdale, Eric J.; Vong, Binh G.; Li, Hongmei; Kim, Sun Hee; Chowdhury, Chinmay; Theodorakis, Emmanuel A.
Tetrahedron, 2003 , vol. 59, # 35 p. 6873 - 6887
反应条件
1: K2CO3; CuI; KI / acetone / 0.5 h / Heating
2: dimethylformamide / 10 h / 140 °C
View Scheme
参考文献
Tisdale, Eric J.; Li, Hongmei; Vong, Binh G.; Kim, Sun Hee; Theodorakis, Emmanuel A.
Organic Letters, 2003 , vol. 5, # 9 p. 1491 - 1494
反应条件
1.1: 25 percent / HCl / 3 h / 0 - 25 °C
2.1: K2CO3; KI; CuI / acetone / 1 h / Heating
2.2: 90 percent / acetone; dimethylformamide / 15 h / 150 °C
View Scheme
参考文献
Tisdale, Eric J.; Vong, Binh G.; Li, Hongmei; Kim, Sun Hee; Chowdhury, Chinmay; Theodorakis, Emmanuel A.
Tetrahedron, 2003 , vol. 59, # 35 p. 6873 - 6887
