3,5-双(1,1,1,3,3,3-六氟-2-羟基丙基)碘苯合成路线 （共 5 条）
反应条件
sulfuric acid; iodine
7 h; Ambient temperature;
参考文献
Fujiki, Kanji; Kashiwagi, Mitsuyoshi; Miyamoto, Hideyuki; Sonoda, Akinari; Ichikawa, Junji; et al.
Journal of Fluorine Chemistry, 1992 , vol. 57, p. 307 - 321
反应条件
sulfur trioxide; iodine in sulfuric acid
参考文献
Soulen, Robert L.; Griffith, James R.
Journal of Fluorine Chemistry, 1989 , vol. 44, p. 203 - 210
反应条件
1: 86 percent / AlCl3 / 6 h / 50 - 54 °C
2: 77 percent / H2SO4, SO3, I2 / 2 h / 70 - 72 °C
View Scheme
参考文献
Sepiol, Janiusz; Soulen, Robert L.
Journal of Fluorine Chemistry, 1984 , vol. 24, p. 61 - 74
反应条件
2: 62 percent / 1.) butyl lithium; 2.) 1.7 N hydrochloric acid / hexane / 50 °C
View Scheme
参考文献
Soulen, Robert L.; Griffith, James R.
Journal of Fluorine Chemistry, 1989 , vol. 44, p. 203 - 210
反应条件
sodium hydride
1.) DMF, 2.) DMF, 40 deg C, 15 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Fujiki, Kanji; Kashiwagi, Mitsuyoshi; Miyamoto, Hideyuki; Sonoda, Akinari; Ichikawa, Junji; et al.
Journal of Fluorine Chemistry, 1992 , vol. 57, p. 307 - 321
