1-(2-甲基苯甲基)哌嗪合成路线 (共 6 条)
反应条件
in tetrahydrofuran 4 h; Reflux;
参考文献
Zhang, Cunlong; Tan, Chunyan; Zu, Xuyu; Zhai, Xin; Liu, Feng; Chu, Bizhu; Ma, Xiaohua; Chen, Yuzong; Gong, Ping; Jiang, Yuyang
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1404 - 1414
反应条件
1: K2CO3 / ethanol / Heating 2: TFA / CH2Cl2 / Ambient temperature View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 6, # 10 p. 1731 - 1743
参考文献
Industrie Chimique Belge, , vol. 22, p. 409,416
反应条件
sodium hydroxide in methanol; diethyl ether; chloroform; sulfuric acid
参考文献
Rhone-Poulenc Sante
Patent: US4769366 A1, 1988 ;
反应条件
triethylamine; xylene
参考文献
Morren et al.
Industrie Chimique Belge, 1957 , vol. 22, p. 409,416