反应条件
1: 1.) THF, EtMgBr, RT, 1 h; 2.) diethyl ether, -25 deg C for 45 min then 1 h at RT then 15 min at 30 deg C
2: 81 percent / p-toluenesulfonic acid / benzene / Heating
3: 1.) BuLi / 1.) THF, -65 deg C, 30 min; 2.) THF, overnight, from -65 deg C to 25 deg C
4: H2SO4 / acetone; H2O / 5 h / Heating
View Scheme
参考文献
Kruithof, Klaas J. H.; Schmitz, Robert F.; Klumpp, Gerhard W.
Tetrahedron, 1983 , vol. 39, # 19 p. 3073 - 3082
