9-去[(4-氯苯基)亚甲基]-9-氧代苯芴醇合成路线 （共 5 条）
反应条件
oxygen; sodium hydroxide in ethanol
T=23 - 70°C; 6 h;
参考文献
Beutler, Ulrich; Fuenfschilling, Peter C.; Steinkemper, Andreas
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 341 - 345
反应条件
1: AlCl3, aluminium chloride / dichloromethane / -5 - 0 °C
2: sodium tetrahydroborate / ethanol / 1 h / -5 - 5 °C
3: sodium tetrahydroborate / ethanol / 3 h / 140 °C
4: sodium hydroxide; oxygen / ethanol / 6 h / 23 - 70 °C
View Scheme
参考文献
Beutler, Ulrich; Fuenfschilling, Peter C.; Steinkemper, Andreas
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 341 - 345
反应条件
1: chlorine / acetic acid / 15 h / 35 - 45 °C
2: AlCl3, aluminium chloride / dichloromethane / -5 - 0 °C
3: sodium tetrahydroborate / ethanol / 1 h / -5 - 5 °C
4: sodium tetrahydroborate / ethanol / 3 h / 140 °C
5: sodium hydroxide; oxygen / ethanol / 6 h / 23 - 70 °C
View Scheme
参考文献
Beutler, Ulrich; Fuenfschilling, Peter C.; Steinkemper, Andreas
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 341 - 345
反应条件
1: ethanol / 15 h / 78 °C
2: sodium hydroxide; oxygen / ethanol / 6 h / 23 - 70 °C
View Scheme
参考文献
Beutler, Ulrich; Fuenfschilling, Peter C.; Steinkemper, Andreas
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 341 - 345
参考文献
Atkinson; Granchelli
Journal of Medicinal Chemistry, 1974 , vol. 17, # 9 p. 1009 - 1012
