1-(3-氯苯基)-2,2-二甲基-1-丙酮合成路线 （共 4 条）
反应条件
1: With copper(l) chloride in tetrahydrofuran
20 h; Heating / reflux;
2: With hydrogenchloride in tetrahydrofuran; water
T=20°C;
3: With water; hydrogenchloride
T=90°C; 1 h;
参考文献
Meyer, Adam Gerhard; Winzenberg, Kevin Norman; Sawutz, David G.; Liepa, Andris Juris
Patent: US2006/63841 A1, 2006 ;
Location in patent: Page/Page column 33-34; 8/12 ;
反应条件
1: 1-bromo-3-chlorobenzene With magnesium; lithium chloride in tetrahydrofuran
T=25°C; 0.166667 h; Inert atmosphere;
2: With CCl2CuN(2-)*2Li(1+) in tetrahydrofuran
T=-10°C; 0.25 h; Inert atmosphere;
3: pivaloyl chloride in tetrahydrofuran
T=25°C; 1 h; Inert atmosphere;
参考文献
Piller, Fabian M.; Metzger, Albrecht; Schade, Matthias A.; Haag, Benjamin A.; Gavryushin, Andrei; Knochel, Paul
Chemistry - A European Journal, 2009 , vol. 15, # 29 p. 7192 - 7202
反应条件
in 1,2-dichloro-benzene
T=180°C; 5 h; Inert atmosphere;
参考文献
Lo Fiego, Marcos J.; Lockhart, Maria T.; Chopa, Alicia B.
Journal of Organometallic Chemistry, 2009 , vol. 694, # 22 p. 3674 - 3678
反应条件
(i), (ii) (oxidation); Multistep reaction;
参考文献
Seguin,J.-P. et al.
Bulletin de la Societe Chimique de France, 1974 , p. 167 - 172
