3-乙氧基-2-环己烯-1-酮合成路线 （共 132 条）
反应条件
(i) Mg, Et2O, (ii) /BRN= 2042049/; Multistep reaction;
参考文献
Julia,M.; Descoins,C.
Bulletin de la Societe Chimique de France, 1970 , p. 1805 - 1815
反应条件
diethyl ether
Eintragen des Reaktionsgemisches in wss. H2SO4 und anschliessend Erhitzen;
参考文献
Woods; Tucker
Journal of the American Chemical Society, 1948 , vol. 70, p. 3340
反应条件
in tetrahydrofuran; diethyl ether
T=0 - 20°C; Inert atmosphere;
参考文献
Lifchits, Olga; Mahlau, Manuel; Reisinger, Corinna M.; Lee, Anna; Fares, Christophe; Polyak, Iakov; Gopakumar, Gopinadhanpillai; Thiel, Walter; List, Benjamin
Journal of the American Chemical Society, 2013 , vol. 135, # 17 p. 6677 - 6693
反应条件
in tetrahydrofuran; pentane
T=-78°C; Inert atmosphere;
参考文献
Coote, Susannah C.; O'Brien, Peter; Whitwood, Adrian C.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 23 p. 4299 - 4314
反应条件
diethyl ether
Eintragen des Reaktionsgemisches in wss. H2SO4 und anschliessendes Destillieren mit Wasser-Dampf;
参考文献
Woods et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 2028
反应条件
1: in diethyl ether
T=0 - 20°C; Inert atmosphere;
2: With hydrogenchloride in water
T=20°C; Inert atmosphere;
参考文献
Shintani, Ryo; Takeda, Momotaro; Nishimura, Takahiro; Hayashi, Tamio
Angewandte Chemie - International Edition, 2010 , vol. 49, # 23 p. 3969 - 3971
反应条件
in tetrahydrofuran
T=0 - 25°C;
参考文献
MERCK and CO., INC.
Patent: WO2007/75749 A2, 2007 ;
Location in patent: Page/Page column 54 ;
反应条件
1: in tetrahydrofuran
T=20°C; 48 h;
2: With hydrogenchloride; water in tetrahydrofuran
参考文献
Scheuermann Nee Taylor, Caroline J.; Jaekel, Christoph
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 17 p. 2708 - 2714
反应条件
in diethyl ether; hexane
1 h; Heating;
参考文献
Wittek, Mechtild; Voegtle, Fritz
Chemische Berichte, 1982 , vol. 115, # 7 p. 2533 - 2539
反应条件
magnesium
1.) Et2O, RT, 1 h, 2.) Et2O, RT, 2 h; Yield given. Multistep reaction;
参考文献
Nioche, J. Y.; Decerprit, J.; Festal, D.
European Journal of Medicinal Chemistry, 1995 , vol. 30, # 5 p. 377 - 386
