3-乙氧基-2-环己烯-1-酮合成路线 （共 132 条）
参考文献
Kakiuchi, Kiyomi; Kumanoya, Shuichi; Ue, Masaki; Tobe, Yoshito; Odaira, Yoshinobu
Chemistry Letters, 1985 , p. 989 - 992
反应条件
(i) LDA, (ii) /BRN= 1098377/, HMPT; Multistep reaction;
参考文献
Pfizer Inc.
Patent: US4371720 A1, 1983 ;
反应条件
lithium diisopropyl amide
T=-78°C;
参考文献
Cossy, Janine; Furet, Nathalie; BouzBouz, Samir
Tetrahedron, 1995 , vol. 51, # 43 p. 11751 - 11764
反应条件
lithium diisopropyl amide
T=-78°C;
参考文献
Schinzer, Dieter; Solyom, Sandor; Becker, Marion
Tetrahedron Letters, 1985 , vol. 26, # 15 p. 1831 - 1834
反应条件
1: LDA / -78 °C
2: LiAlH4
View Scheme
参考文献
Cossy, Janine; Furet, Nathalie; BouzBouz, Samir
Tetrahedron, 1995 , vol. 51, # 43 p. 11751 - 11764
反应条件
1: 1.) lithium diisopropylamide, hexamethylphosphoramide / 1.) -78 deg C
2: 83 percent / 20percent sulphuric acid / tetrahydrofuran / 1 h
3: acetic anhydride / 52 h / 25 °C
4: 2.) 5percent sodium hydroxide / 1.) hexane, irradiation, 10 h, 2.) ethanol, 0 deg C, 2 h
View Scheme
参考文献
Begley, Michael J.; Mellor, Michael; Pattenden, Gerald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1905 - 1912
反应条件
1: 1.) lithium diisopropylamide, hexamethylphosphoramide / 1.) -78 deg C
2: 83 percent / 20percent sulphuric acid / tetrahydrofuran / 1 h
3: acetic anhydride / 52 h / 25 °C
View Scheme
参考文献
Begley, Michael J.; Mellor, Michael; Pattenden, Gerald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1905 - 1912
反应条件
1: 1.) lithium diisopropylamide, hexamethylphosphoramide / 1.) -78 deg C
2: 83 percent / 20percent sulphuric acid / tetrahydrofuran / 1 h
3: acetic anhydride / 52 h / 25 °C
View Scheme
参考文献
Begley, Michael J.; Mellor, Michael; Pattenden, Gerald
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1905 - 1912
反应条件
(i) Li, Na, hexane, (ii) /BRN= 2042049/; Multistep reaction;
参考文献
Fetizon,M. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 1407 - 1410
反应条件
1.1: LDA / tetrahydrofuran / 1 h / 20 °C
1.2: 55 percent / tetrahydrofuran / -78 - 20 °C
2.1: DIBAL-H / diethyl ether; hexane / 0.5 h
2.2: 79 percent / aq. TsOH / diethyl ether / 1 h
View Scheme
参考文献
Fagnoni, Maurizio; Schmoldt, Philip; Kirschberg, Thorsten; Mattay, Jochen
Tetrahedron, 1998 , vol. 54, # 23 p. 6427 - 6444
