2-(乙酰氨基)-4-甲基吡啶合成路线 （共 22 条）
反应条件
1: potassium permanganate 2: HCl View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 23 p. 5978 - 5981
反应条件
1: aq. KMnO4 / 10 h / 75 °C 2: 10percent NaOH View Scheme
参考文献
Ferrari; Marcon
Farmaco, Edizione Scientifica, 1958 , vol. 13, p. 485,487
反应条件
1: KMnO4; H2O 2: methanol. HCl 3: acetic acid 4: concentrated aqueous NH3 5: concentrated aqueous NH3 / 130 °C View Scheme
参考文献
Farmaco, Edizione Scientifica, , vol. 13, p. 485,487
反应条件
1: KMnO4 / H2O / Heating 2: SOCl2 / methanol / Heating View Scheme
参考文献
Ferrari; Marcon
Farmaco, Edizione Scientifica, 1958 , vol. 13, p. 485,487
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide T=0°C; 0.5 h;
参考文献
ISHIHARA SANGYO KAISHA, LTD.
Patent: WO2009/88103 A1, 2009 ;
Location in patent: Page/Page column 15 ;
反应条件
bromine in dichloromethane
反应条件
1: potassium permanganate / water / 60 °C
2: boron trifluoride diethyl etherate / ethanol / Reflux
View Scheme
参考文献
ASCEPION PHARMACEUTICALS, INC.; JIANG, Shan; GAO, Xiaoyong; WANG, Qishan
Patent: WO2012/28106 A1, 2012 ;
WO 2012/028106 A1
反应条件
acetic acid
Erhitzen des Reaktionsprodukts mit wss. NaOH;
参考文献
Brown
Journal of the American Chemical Society, 1957 , vol. 79, p. 3565
反应条件
1: aq. KMnO4 / 10 h / 75 °C
2: 10percent NaOH
3: concd. H2SO4, fuming HNO3 / 0.33 h / 0 °C
4: 95 percent / concd. H2SO4 / 0 - 20 °C
View Scheme
参考文献
Deady, Leslie W.; Korytsky, Olga L.; Rowe, Jeffrey E.
Australian Journal of Chemistry, 1982 , vol. 35, # 10 p. 2025 - 2034
反应条件
1: KMnO4; H2O
2: methanol. HCl
3: acetic acid
View Scheme
参考文献
Ferrari; Marcon
Farmaco, Edizione Scientifica, 1958 , vol. 13, p. 485,487
