2-(乙酰氨基)-4-甲基吡啶合成路线 （共 22 条）
反应条件
1.1: 42 percent / potassium permanganate / H2O / 2.5 h / 50 - 90 °C
2.1: carbonyldiimidazole / dimethylformamide / 0.75 h / 20 °C
2.2: 65 percent / potassium tert-butoxide / dimethylformamide / 2 h / 120 °C
3.1: 55 percent / HBr / H2O / 30 h / Heating
View Scheme
参考文献
Wagner, Gerd K.; Kotschenreuther, Dunja; Zimmermann, Werner; Laufer, Stefan A.
Journal of Organic Chemistry, 2003 , vol. 68, # 11 p. 4527 - 4530
反应条件
1: acetic acid / Erhitzen des Reaktionsprodukts mit wss. NaOH
2: concentrated sulfuric acid; aqueous hydrogen peroxide; sulfur trioxide
View Scheme
参考文献
Brown
Journal of the American Chemical Society, 1957 , vol. 79, p. 3565
