2-乙酰氨基-6-甲基嘧啶合成路线 （共 34 条）
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane; water 1.5 h; Heatingirradiation;
参考文献
Journal of Heterocyclic Chemistry, , vol. 38, # 1 p. 173 - 178
反应条件
1: N-(6-methyl-pyridin-2-yl)acetamide With N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane Heatingirradiation; 2: sodium acetate in N,N-dimethyl-formamide T=80 - 90°C; 12 h;
参考文献
Goswami; Ghosh; Mukherjee; Avijit Kumar Adak; Ajit Kumar Mahapatra
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 1 p. 173 - 178
反应条件
N-bromosuccinmide 0.05 h; microwave irradiation;
参考文献
Chemistry Letters, , vol. 33, # 7 p. 916 - 917
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane Heatingirradiation; Title compound not separated from byproducts;
参考文献
Goswami; Ghosh; Mukherjee; Avijit Kumar Adak; Ajit Kumar Mahapatra
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 1 p. 173 - 178
反应条件
1: KMnO4; H2O 2: methanol; HCl 3: concentrated aqueous NH3 View Scheme
参考文献
Ferrari; Marcon
Farmaco, Edizione Scientifica, 1959 , vol. 14, p. 594,596
反应条件
1: KMnO4; H2O 2: methanol; HCl 3: acetic acid 4: concentrated aqueous NH3 View Scheme
参考文献
Ferrari; Marcon
Farmaco, Edizione Scientifica, 1959 , vol. 14, p. 594,596
反应条件
1: 16.5 g / KMnO4 / H2O / 3 h / 75 °C 2: HCl / Heating 3: 25 percent / Br2 / CHCl3 4: 85 percent / 9M H2SO4, NaNO2 / H2O / 0.25 h / 0 °C View Scheme
参考文献
Kelly, T. Ross; Lang, Fengrui
Journal of Organic Chemistry, 1996 , vol. 61, # 14 p. 4623 - 4633
反应条件
1: 16.5 g / KMnO4 / H2O / 3 h / 75 °C 2: HCl / Heating 3: 25 percent / Br2 / CHCl3 View Scheme
参考文献
F. HOFFMANN-LA ROCHE AG; BAUMANN, Karlheinz; GOETSCHI, Erwin; GREEN, Luke; JOLIDON, Synese; KNUST, Henner; LIMBERG, Anja; LUEBBERS, Thomas; THOMAS, Andrew
Patent: WO2011/92272 A1, 2011 ;
WO 2011/092272 A1
反应条件
1.1: water; potassium permanganate / 4 h / 75 °C 1.2: pH 4 - 5 2.1: hydrogenchloride / methanol / 18 h / Reflux 3.1: bromine / chloroform / 40 h / 20 °C View Scheme
参考文献
F. HOFFMANN-LA ROCHE AG; BAUMANN, Karlheinz; FLOHR, Alexander; GOETSCHI, Erwin; GREEN, Luke; JOLIDON, Synese; KNUST, Henner; LIMBERG, Anja; LUEBBERS, Thomas; THOMAS, Andrew
Patent: WO2011/101304 A2, 2011 ;
WO 2011/101304 A2
反应条件
1: KMnO4 2: 61 percent / aq. NaOH / 1 h / Heating View Scheme
参考文献
Deady, Leslie W.; Korytsky, Olga L.; Rowe, Jeffrey E.
Australian Journal of Chemistry, 1982 , vol. 35, # 10 p. 2025 - 2034
