4-(3-呋喃基)-3,6-二氢-1(2H)-吡啶羧酸叔丁酯合成路线 （共 2 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethylene glycol dimethyl ether
T=80°C; 0.333333 h; Inert atmosphereMicrowave irradiation;
参考文献
JANSSEN RandD IRELAND; GUILLEMONT, Jerôme Emile Georges; LANÇOIS, David Francis Alain; MOTTE, Magali Madeleine Simone; BALEMANS, Wendy Mia Albert; KOUL, Anil
Patent: WO2014/23815 A1, 2014 ;
Location in patent: Page/Page column 40 ;
反应条件
1.1: N-ethyl-N,N-diisopropylamine; n-butyllithium / hexane; tetrahydrofuran / 0.5 h / -78 °C / |Inert atmosphere
1.2: -78 - 20 °C / |Inert atmosphere
2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethylene glycol dimethyl ether / 0.33 h / 80 °C / |Inert atmosphere; |Microwave irradiation
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参考文献
JANSSEN RandD IRELAND; GUILLEMONT, Jerôme, Emile, Georges; LANÇOIS, David, Francis, Alain; MOTTE, Magali, Madeleine, Simone; KOUL, Anil; BALEMANS, Wendy, Mia, Albert
Patent: WO2013/21052 A1, 2013 ;
WO 2013/021052 A1
