6,7-二氢-5H-环戊并[c]吡啶合成路线 （共 8 条）
反应条件
hydrogen; sodium acetate; palladium dichloride in ethanol
P=2482.31 Torr; 20 h;
参考文献
Guandalini, Luca; Dei, Silvia; Gualtieri, Fulvio; Romanelli, Maria Novella; Scapecchi, Serena; Teodori, Elisabetta; Varani, Katia
Helvetica Chimica Acta, 2002 , vol. 85, # 1 p. 96 - 107
反应条件
pyrrolidine in chloroform
T=45°C; 20 h;
参考文献
Boger, Dale L.; Panek, James S.; Meier, Michael M.
Journal of Organic Chemistry, 1982 , vol. 47, # 5 p. 895 - 897
反应条件
in chloroform
1.) 25 deg C, 1.5 h, 2.) 45 deg C, 35 h;
参考文献
Boger, Dale L.; Panek, James S.
Journal of Organic Chemistry, 1981 , vol. 46, # 10 p. 2179 - 2182
反应条件
1: 92 percent / H2 / Pd/C / ethanol / 1034.3 Torr
2: DIBALH / toluene / 4 h
3: NH2OH*HCl / acetic acid / 4 h / Heating
View Scheme
参考文献
Guandalini, Luca; Dei, Silvia; Gualtieri, Fulvio; Romanelli, Maria Novella; Scapecchi, Serena; Teodori, Elisabetta; Varani, Katia
Helvetica Chimica Acta, 2002 , vol. 85, # 1 p. 96 - 107
反应条件
1: 69 percent / toluene / 5 h / Heating
2: 92 percent / H2 / Pd/C / ethanol / 1034.3 Torr
3: DIBALH / toluene / 4 h
4: NH2OH*HCl / acetic acid / 4 h / Heating
View Scheme
参考文献
Guandalini, Luca; Dei, Silvia; Gualtieri, Fulvio; Romanelli, Maria Novella; Scapecchi, Serena; Teodori, Elisabetta; Varani, Katia
Helvetica Chimica Acta, 2002 , vol. 85, # 1 p. 96 - 107
反应条件
in chloroform
T=45°C; 39 h;
参考文献
Boger, Dale L.; Panek, James S.
Journal of Organic Chemistry, 1981 , vol. 46, # 10 p. 2179 - 2182
反应条件
hydroxylamine hydrochloride in acetic acid
4 h; Heating;
参考文献
Guandalini, Luca; Dei, Silvia; Gualtieri, Fulvio; Romanelli, Maria Novella; Scapecchi, Serena; Teodori, Elisabetta; Varani, Katia
Helvetica Chimica Acta, 2002 , vol. 85, # 1 p. 96 - 107
反应条件
1: phosphoryl chloride / 180 °C
2: Raney nickel; sodium methylate; methanol / 20 °C / Hydrogenation
View Scheme
参考文献
Prelog; Metzler
Helvetica Chimica Acta, 1946 , vol. 29, p. 1170,1173
