1: 3-phenyl-3-hydroxypropene With α-cyclohexylcyclohexanemethanamine; tetrabutylammomium bromide in water T=20°C; Heck reaction; 0.25 h; 2: 2-iodophenol With 4'-hydroxyacetophenone oxime palladacycle catalyst in water T=120°C; Heck reaction; 14 h; Further stages. Further byproducts. Title compound not separated from byproducts.;
参考文献
Alacid, Emilio; Najera, Carmen
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2572 - 2584
1: potassium carbonate; palladium 10 on activated carbon / water / 2.5 h / 80 °C / |Inert atmosphere 2: potassium carbonate; palladium 10 on activated carbon / water / 2.5 h / 80 °C / |Inert atmosphere View Scheme
参考文献
Schmidt, Bernd; Riemer, Martin
Journal of Organic Chemistry, 2014 , vol. 79, # 9 p. 4104 - 4118
