2-(噻吩-2-基)丙-2-醇合成路线 （共 4 条）
反应条件
1: thiophene With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in hexane
T=0°C; 1 h; Cooling with ice;
2: acetone in tetrahydrofuran; hexane
T=0°C; 0.25 h; Cooling with ice;
参考文献
Gupta, Iti; Froehlich, Roland; Ravikanth, Mangalampalli
European Journal of Organic Chemistry, 2008 , # 11 p. 1884 - 1900
参考文献
Bargar, Thomas M.; Broersma, Robert J.; Creemer, Lawrence C.; McCarthy, James R.; Hornsperger, Jean-Marie; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 3 p. 315 - 317
参考文献
Thomas
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1908 , vol. 146, p. 643
Bulletin de la Societe Chimique de France, 1909 , vol. <4> 5, p. 731
反应条件
1: KHSO4
2: 1.) NCS, (PhSe)2, pyr / 2.) DMF, 90 deg C
3: NH2NH2*H2O / ethanol
View Scheme
参考文献
Bargar, Thomas M.; Broersma, Robert J.; Creemer, Lawrence C.; McCarthy, James R.; Hornsperger, Jean-Marie; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 3 p. 315 - 317
