6-甲基磺酰基-1H-吡唑并[3,4-d]嘧啶-4-醇合成路线 （共 4 条）
反应条件
1: N,N-dimethyl-aniline; POCl3 2: palladium/charcoal; aq.-ethanolic NH3 / Hydrogenation View Scheme
参考文献
Robins
Journal of the American Chemical Society, 1956 , vol. 78, p. 784,787
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6413
反应条件
N,N-dimethyl-aniline; trichlorophosphate
参考文献
Kim, Dong Chan; Lee, Yeo Ran; Yang, Beom-Seok; Shin, Kye Jung; Kim, Dong Jin; Chung, Bong Young; Yoo, Kyung Ho
European Journal of Medicinal Chemistry, 2003 , vol. 38, # 5 p. 525 - 532
反应条件
1: 92 percent / POCl3; PhNMe2
2: 95 percent / iPr2NEt / butan-1-ol / 24 h / 50 °C
View Scheme
参考文献
Kim, Dong Chan; Lee, Yeo Ran; Yang, Beom-Seok; Shin, Kye Jung; Kim, Dong Jin; Chung, Bong Young; Yoo, Kyung Ho
European Journal of Medicinal Chemistry, 2003 , vol. 38, # 5 p. 525 - 532
反应条件
1: N,N-dimethyl-aniline; POCl3
2: H2O; NH3 / 100 °C
View Scheme
参考文献
Robins
Journal of the American Chemical Society, 1956 , vol. 78, p. 784,787
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6413
