2,2 '-二氯-4,4 '-二吡啶合成路线 （共 15 条）
反应条件
1: With n-butyllithium; trimethylstannyl chloride 2: 2-Chloro-4-iodo-pyridine With tetrakis(triphenylphosphine) palladium(0)
参考文献
ASTRAZENECA AB
Patent: WO2004/52880 A1, 2004 ;
Location in patent: Page 30-31 ;
WO 2004/052880 A1
反应条件
1: CsI / 0.5 h 2: 70percent HClO4 / ethanol View Scheme
参考文献
European Journal of Inorganic Chemistry, , # 6 p. 771 - 781
反应条件
copper(l) iodide; cesium fluoride in N,N-dimethyl-formamide T=120°C; Hiyama Coupling; 12 h; Inert atmosphere;
参考文献
Gurung, Santosh K.; Thapa, Surendra; Vangala, Adarsh S.; Giri, Ramesh
Organic Letters, 2013 , vol. 15, # 20 p. 5378 - 5381
反应条件
copper(l) iodide; cesium fluoride in N,N-dimethyl-formamide T=120°C; Hiyama Coupling; 12 h; Inert atmosphere;
参考文献
Gurung, Santosh K.; Thapa, Surendra; Vangala, Adarsh S.; Giri, Ramesh
Organic Letters, 2013 , vol. 15, # 20 p. 5378 - 5381
反应条件
copper(l) iodide; cesium fluoride in N,N-dimethyl-formamide T=120°C; Hiyama Coupling; 12 h; Inert atmosphere;
参考文献
Gurung, Santosh K.; Thapa, Surendra; Vangala, Adarsh S.; Giri, Ramesh
Organic Letters, 2013 , vol. 15, # 20 p. 5378 - 5381
反应条件
copper(l) iodide; cesium fluoride in N,N-dimethyl-formamide T=120°C; Hiyama Coupling; 12 h; Inert atmosphere;
参考文献
Gurung, Santosh K.; Thapa, Surendra; Vangala, Adarsh S.; Giri, Ramesh
Organic Letters, 2013 , vol. 15, # 20 p. 5378 - 5381
反应条件
copper(l) iodide; cesium fluoride in N,N-dimethyl-formamide T=120°C; Hiyama Coupling; 12 h; Inert atmosphere;
参考文献
Gurung, Santosh K.; Thapa, Surendra; Vangala, Adarsh S.; Giri, Ramesh
Organic Letters, 2013 , vol. 15, # 20 p. 5378 - 5381
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-60°C; 0.25 h; Inert atmosphere; 2: With iodine in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphere; Reagent/catalystTemperature;
参考文献
Journal of Organic Chemistry, , vol. 78, # 15 p. 7683 - 7689
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-60°C; 0.416667 h; Inert atmosphere; 2: With iodine in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 78, # 15 p. 7683 - 7689
反应条件
1: 31 percent / m-chloroperbenzoic acid (mcpba) / CHCl3 / 480 h / Ambient temperature 2: CsI / 0.5 h 3: 70percent HClO4 / ethanol View Scheme
参考文献
European Journal of Inorganic Chemistry, , # 6 p. 771 - 781
