N-苄氧羰基-L-亮氨酸 二环己基铵盐合成路线 （共 6 条）
反应条件
triethylamine in water Ambient temperature;
参考文献
Azuse; Tamura; Kinomura; Okai; Kouge; Hamatsu; Koizumi
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 10 p. 3103 - 3108
反应条件
sodium hydroxide 1.) ca 5 deg C, 15 min 2.) ethyl acetate, Et2O, 5 min; Multistep reaction;
参考文献
Tetrahedron, , vol. 46, # 15 p. 5325 - 5332
反应条件
benzotriazol-1-ol; dicyclohexyl-carbodiimide in dichloromethane 2 h; temperature: below 0 deg C;
参考文献
Hoogwater, D. A.; Peereboom, M.
Tetrahedron, 1990 , vol. 46, # 15 p. 5325 - 5332
反应条件
4-methyl-morpholine; chloroformic acid ethyl ester 1.) THF, -15 deg C, 5 min, 2.) CH2Cl2, -15 deg C, 4 h; room temperature, overnight; Yield given. Multistep reaction;
参考文献
Nakata; Takahashi; Nakatani; Kuramitsu; Tamura; Okai
Bioscience, biotechnology, and biochemistry, 1995 , vol. 59, # 4 p. 689 - 693
反应条件
sulfuric acid in water; ethyl acetate Cooling with ice;
参考文献
Loeser, Reik; Frizler, Maxim; Schilling, Klaus; Guetschow, Michael
Angewandte Chemie - International Edition, 2008 , vol. 47, # 23 p. 4331 - 4334
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine; thionyl chloride
1.) CH2Cl2, room temperature, 1 min, 2.) CH2Cl2, room temperature, 20 min; Yield given. Multistep reaction;
参考文献
Matsuda, Fuyuhiko; Itoh, Shin; Hattori, Noritaka; Yanagiya, Mitsutoshi; Matsumoto, Takeshi
Tetrahedron, 1985 , vol. 41, # 18 p. 3625 - 3631
