2-(苯基甲基)-肼羧酸 1,1-二甲基乙酯合成路线 （共 18 条）
反应条件
hydrogenchloride in tetrahydrofuran 0.166667 h; Heating; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 46, # 26 p. 5413 - 5414
反应条件
hydrogen; palladium on activated charcoal in methanol
P=1551.44 Torr; 0.333333 h;
参考文献
Melendez, Rosa E.; Lubell, William D.
Journal of the American Chemical Society, 2004 , vol. 126, # 21 p. 6759 - 6764
反应条件
1: 89 percent / diethyl ether / 16 h
2: 92 percent / H2 / Pd/C / methanol / 0.33 h / 1551.44 Torr
View Scheme
参考文献
Melendez, Rosa E.; Lubell, William D.
Journal of the American Chemical Society, 2004 , vol. 126, # 21 p. 6759 - 6764
反应条件
1: 78.1 percent / hydrazine monohydrate / propan-2-ol / 0.33 h / 20 °C
2: 89 percent / diethyl ether / 16 h
3: 92 percent / H2 / Pd/C / methanol / 0.33 h / 1551.44 Torr
View Scheme
参考文献
Melendez, Rosa E.; Lubell, William D.
Journal of the American Chemical Society, 2004 , vol. 126, # 21 p. 6759 - 6764
反应条件
1: 89 percent / diethyl ether / 16 h
2: 92 percent / H2 / Pd/C / methanol / 0.33 h / 1551.44 Torr
View Scheme
参考文献
Melendez, Rosa E.; Lubell, William D.
Journal of the American Chemical Society, 2004 , vol. 126, # 21 p. 6759 - 6764
反应条件
in toluene
T=20°C; 72 h;
参考文献
Armstrong, Alan; Jones, Lyn H.; Knight, Jamie D.; Kelsey, Richard D.
Organic Letters, 2005 , vol. 7, # 4 p. 713 - 716
反应条件
4-methyl-morpholine in dichloromethane
T=10 - 20°C; 18 h;
参考文献
Baburaj, Thankappan; Thambidurai, Sivalingam
Synlett, 2011 , # 14 art. no. B08111ST, p. 1993 - 1996
反应条件
in N,N-dimethyl-formamide
3 h;
参考文献
Marastoni, Mauro; Bergonzoni, Manuela; Bortolotti, Fabrizio; Tomatis, Roberto
Arzneimittel-Forschung/Drug Research, 1997 , vol. 47, # 7 p. 889 - 892
反应条件
1: 100 percent / tetrahydrofuran / 24 h / Heating
2: 40 percent / Oxone(R); NaHCO3 / acetonitrile; H2O / 23 h / 20 °C
3: 52 percent / CH2Cl2 / 25.5 h / 20 °C
View Scheme
参考文献
Armstrong, Alan; Jones, Lyn H.; Knight, Jamie D.; Kelsey, Richard D.
Organic Letters, 2005 , vol. 7, # 4 p. 713 - 716
反应条件
1: 40 percent / Oxone(R); NaHCO3 / acetonitrile; H2O / 23 h / 20 °C
2: 52 percent / CH2Cl2 / 25.5 h / 20 °C
View Scheme
参考文献
Armstrong, Alan; Jones, Lyn H.; Knight, Jamie D.; Kelsey, Richard D.
Organic Letters, 2005 , vol. 7, # 4 p. 713 - 716
