2-苯基-4-[4-三氟甲基苯基]噻唑合成路线 （共 3 条）
反应条件
1: 78 percent / oleum / 4 h / -5 °C 2: 97 percent / thionyl chloride; DMF / acetonitrile / 3.5 h / 20 °C View Scheme
参考文献
Ikemoto, Norihiro; Liu, Jinchu; Brands, Karel M.J.; McNamara, James M.; Reider, Paul J.
Tetrahedron, 2003 , vol. 59, # 8 p. 1317 - 1325
反应条件
in isopropyl alcohol
T=27°C; 2 h;
参考文献
Ikemoto, Norihiro; Liu, Jinchu; Brands, Karel M.J.; McNamara, James M.; Reider, Paul J.
Tetrahedron, 2003 , vol. 59, # 8 p. 1317 - 1325
反应条件
1: conc. HBr; bromine / acetic acid / 1.5 h / 15 °C
2: 93 percent / propan-2-ol / 2 h / 27 °C
View Scheme
参考文献
Ikemoto, Norihiro; Liu, Jinchu; Brands, Karel M.J.; McNamara, James M.; Reider, Paul J.
Tetrahedron, 2003 , vol. 59, # 8 p. 1317 - 1325
