2-(苄氧基)-5-甲基苯甲醛合成路线 （共 8 条）
反应条件
sodium hydride in N,N-dimethyl-formamide; mineral oil
Inert atmosphere;
参考文献
Mori, Keiji; Kawasaki, Taro; Sueoka, Shosaku; Akiyama, Takahiko
Organic Letters, 2010 , vol. 12, # 8 p. 1732 - 1735
反应条件
1: 1-((2-bromo-4-methylphenoxy)methyl)benzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 1 h;
2: N,N-dimethyl-formamide in tetrahydrofuran; hexane
T=-78 - 20°C; 12 h; Further stages.;
参考文献
Soegel, Sebastian; Tokunaga, Norihito; Sasaki, Keigo; Okamoto, Kazuhiro; Hayashi, Tamio
Organic Letters, 2008 , vol. 10, # 4 p. 589 - 592
反应条件
silver trifluoromethanesulfonate in dichloromethane
T=-78°C; 0.166667 h; Inert atmosphere;
参考文献
Ohsawa, Kosuke; Yoshida, Masahito; Doi, Takayuki
Journal of Organic Chemistry, 2013 , vol. 78, # 7 p. 3438 - 3444
反应条件
potassium carbonate in ethanol; water
Inert atmosphereReflux;
参考文献
Kobayashi, Kenya; Nishikata, Takashi; Yamamoto, Yasunori; Miyaura, Norio
Bulletin of the Chemical Society of Japan, 2008 , vol. 81, # 8 p. 1019 - 1025
反应条件
tin(IV) chloride in dichloromethane
T=-78°C; 0.166667 h; Reagent/catalyst;
参考文献
Ohsawa, Kosuke; Yoshida, Masahito; Doi, Takayuki
Journal of Organic Chemistry, 2013 , vol. 78, # 7 p. 3438 - 3444
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 5.5 h / 20 °C / |Inert atmosphere
2: tin(IV) chloride / dichloromethane / 0.17 h / -78 °C
View Scheme
参考文献
Ohsawa, Kosuke; Yoshida, Masahito; Doi, Takayuki
Journal of Organic Chemistry, 2013 , vol. 78, # 7 p. 3438 - 3444
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 5.5 h / 20 °C / |Inert atmosphere
2: silver trifluoromethanesulfonate / dichloromethane / 0.17 h / -78 °C / |Inert atmosphere
View Scheme
参考文献
Ohsawa, Kosuke; Yoshida, Masahito; Doi, Takayuki
Journal of Organic Chemistry, 2013 , vol. 78, # 7 p. 3438 - 3444
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 5.5 h / 20 °C / |Inert atmosphere
2: tin(IV) chloride / dichloromethane / 0.17 h / -78 °C
View Scheme
参考文献
Ohsawa, Kosuke; Yoshida, Masahito; Doi, Takayuki
Journal of Organic Chemistry, 2013 , vol. 78, # 7 p. 3438 - 3444
