4-羟基-3-甲氧基-D3-苯基乙二醇合成路线 （共 9 条）
反应条件
ammonium hydroxide; sodium periodate 0.333333 h; determination in urine by phosphorimetric method;
参考文献
Ohkura; Yamaguchi; Kai; Kohashi
Chemical and pharmaceutical bulletin, 1980 , vol. 28, # 6 p. 1913 - 1916
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Benigni,J.D.; Verbiscar,A.J.
Journal of Medicinal Chemistry, 1963 , vol. 6, p. 607 - 608
反应条件
1: (i) aq. HCl, dioxane, (ii) /BRN= 385737/, Py
2: HCl
3: LiAlH4 / tetrahydrofuran
4: H2 / Pd-C / ethanol
View Scheme
参考文献
Benigni,J.D.; Verbiscar,A.J.
Journal of Medicinal Chemistry, 1963 , vol. 6, p. 607 - 608
反应条件
1: HCl
2: LiAlH4 / tetrahydrofuran
3: H2 / Pd-C / ethanol
View Scheme
参考文献
Benigni,J.D.; Verbiscar,A.J.
Journal of Medicinal Chemistry, 1963 , vol. 6, p. 607 - 608
反应条件
1: LiAlH4 / tetrahydrofuran
2: H2 / Pd-C / ethanol
View Scheme
参考文献
Benigni,J.D.; Verbiscar,A.J.
Journal of Medicinal Chemistry, 1963 , vol. 6, p. 607 - 608
反应条件
lithium aluminium tetrahydride in diethyl ether
reflux, 2h; RT, overnight;
参考文献
Holshouser; Kolb
Journal of Pharmaceutical Sciences, 1986 , vol. 75, # 6 p. 619 - 621
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Jerkeman,P.; Lindberg,B.
Acta Chemica Scandinavica (1947-1973), 1964 , vol. 18, p. 1477 - 1482
反应条件
1: NaI / ethanol / Heating
2: BaCO3 / aq. ethanol / Heating
3: H2 / Pd-C / ethanol
View Scheme
参考文献
Jerkeman,P.; Lindberg,B.
Acta Chemica Scandinavica (1947-1973), 1964 , vol. 18, p. 1477 - 1482
反应条件
1: BaCO3 / aq. ethanol / Heating
2: H2 / Pd-C / ethanol
View Scheme
参考文献
Jerkeman,P.; Lindberg,B.
Acta Chemica Scandinavica (1947-1973), 1964 , vol. 18, p. 1477 - 1482
