2,3-二氢-1,5-苯并硫氮杂卓-4(5H)-酮合成路线 （共 24 条）
反应条件
1: 70 percent / Lawesson's reagent / toluene / 1.5 h / 90 - 100 °C 2: 90 percent / butan-1-ol / Heating View Scheme
参考文献
Ambrogi; Grandolini; Rossi; Tiralti
Farmaco, Edizione Scientifica, 1987 , vol. 42, # 8 p. 575 - 583
反应条件
in toluene
2 h; Heating;
参考文献
Rutkauskas; Beresnevicius
Chemistry of Heterocyclic Compounds, 2006 , vol. 42, # 2 p. 227 - 232
反应条件
toluene-4-sulfonic acid in o-xylene
T=125°C; Reflux;
参考文献
Itabashi, Saori; Lu, Rong; Miyakoshi, Tetsuo
Heterocycles, 2011 , vol. 83, # 1 p. 171 - 177
反应条件
sodium hydroxide in water
参考文献
Bayer Aktiengesellschaft
Patent: US4948886 A1, 1990 ;
反应条件
[Hmim]CF3COO
T=80°C; hetero-Michael addition; 4 h;
参考文献
Dabiri, Minoo; Salehi, Peyman; Bahramnejad, Mahboobeh; Baghbanzadeh, Mostafa
Monatshefte fur Chemie, 2012 , vol. 143, # 1 p. 109 - 112
反应条件
[Hmim]CF3COO
T=80°C; hetero-Michael addition; 4 h;
参考文献
Dabiri, Minoo; Salehi, Peyman; Bahramnejad, Mahboobeh; Baghbanzadeh, Mostafa
Monatshefte fur Chemie, 2012 , vol. 143, # 1 p. 109 - 112
参考文献
Levai, Albert; Puzicha, Gisbert
Synthetic Communications, 1985 , vol. 15, # 7 p. 623 - 632
反应条件
Lawesson's reagent in dichloromethane
T=-20°C;
参考文献
Bartsch; Erker
Tetrahedron Letters, 1992 , vol. 33, # 2 p. 199 - 200
反应条件
1: 70 percent / piperidine / toluene / Ambient temperature
2: 95 percent / conc. sulfuric acid / 1 h / Heating
3: 70 percent / Zn powder, acetic acid / methanol / 0.17 h / Heating
4: 30 percent / decahydronaphthalene / Heating
View Scheme
参考文献
Levai, Albert; Puzicha, Gisbert
Synthetic Communications, 1985 , vol. 15, # 7 p. 623 - 632
反应条件
2: aqueous NaHCO3
View Scheme
参考文献
Weinstein et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 363,369
