2,3-二氢-1,5-苯并硫氮杂卓-4(5H)-酮合成路线 （共 24 条）
反应条件
tris-(2-chloro-ethyl)-amine; sulfuric acid in benzene
参考文献
Wuensch,K.-H. et al.
Chemische Berichte, 1970 , vol. 103, p. 2302 - 2307
反应条件
1: 70 percent / Zn powder, acetic acid / methanol / 0.17 h / Heating
2: 30 percent / decahydronaphthalene / Heating
View Scheme
参考文献
Levai, Albert; Puzicha, Gisbert
Synthetic Communications, 1985 , vol. 15, # 7 p. 623 - 632
反应条件
1: 35 percent / piperidine / toluene / Ambient temperature
2: 70 percent / xylene / Heating
View Scheme
参考文献
Levai, Albert; Puzicha, Gisbert
Synthetic Communications, 1985 , vol. 15, # 7 p. 623 - 632
反应条件
1: 77 percent / trifluoroacetic acid / toluene / 72 h / Heating
2: 55 percent / H2O, NaHCO3 / aq. ethanol / 20 h / Heating
View Scheme
参考文献
Walia; Lankin; et al.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 4 p. 1117 - 1119
参考文献
Levai, Albert; Puzicha, Gisbert
Synthetic Communications, 1985 , vol. 15, # 7 p. 623 - 632
反应条件
1: potassium hydroxide / water; ethylene glycol / 140 °C / Reflux
2: ATG / N,N-dimethyl-formamide / 50 °C / Inert atmosphere
3: toluene-4-sulfonic acid / o-xylene / 125 °C / Reflux
View Scheme
参考文献
Itabashi, Saori; Lu, Rong; Miyakoshi, Tetsuo
Heterocycles, 2011 , vol. 83, # 1 p. 171 - 177
反应条件
sodium hydrogencarbonate
参考文献
Weinstein et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 363,369
反应条件
trimethylsilylazide; trifluoroacetic acid
72 h; Ambient temperature;
参考文献
Kaye; Mphahlele
Synthetic Communications, 1995 , vol. 25, # 10 p. 1495 - 1509
反应条件
acetic anhydride
1.) pyridine, room temp., 30 min; Yield given. Multistep reaction;
参考文献
Ambrogi; Grandolini
Synthesis, 1987 , vol. No. 8, p. 724 - 726
反应条件
1: 70 percent / Lawesson's reagent / toluene / 1.5 h / 90 - 100 °C
2: 87 percent / butan-1-ol / Heating
View Scheme
参考文献
Ambrogi; Grandolini; Rossi; Tiralti
Farmaco, Edizione Scientifica, 1987 , vol. 42, # 8 p. 575 - 583
