1.1: 67 percent / NaIO4 / RuCl3 / ethyl acetate; acetonitrile; H2O / 3 h / 20 °C 2.1: 100 percent / methanol / 0.25 h 3.1: LiBH4 / tetrahydrofuran / 8 h / 20 °C 3.2: DMAP; Ac2O / pyridine; CH2Cl2 / 2 h 3.3: aq. HCl / 18 h / Heating View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: 80 percent / m-CPBA / toluene / 24 h / 20 &deg;C<br />2: 63 percent / H₂SO₄; H₂O / dioxane / 2.5 h / Heating<br />3: 100 percent / DMAP / pyridine; CH₂Cl₂ / 2 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 95 percent / NaOAc / Pd₂(dba)3*dba / acetonitrile / 0.33 h<br />2: HCO₂H / ethyl acetate / 0.67 h<br />3: 80 percent / m-CPBA / toluene / 24 h / 20 &deg;C<br />4: 63 percent / H₂SO₄; H₂O / dioxane / 2.5 h / Heating<br />5: 100 percent / DMAP / pyridine; CH₂Cl₂ / 2 h<br /> <br /> &nbsp;