(alphaR)-alpha-甲基-3,5-二(三氟甲基)-苯甲醇乙酸酯合成路线 （共 7 条）
反应条件
hydrogenchloride in methanol Heating;
参考文献
Vankawala, Pravinchandra J.; Kolla, Naveenkumar; Elati, Chandrashekar R.; Sreenivasulu; Kumar, K. Arun; Anjaneyulu, Yerrimilli; Venkatraman, Sundaram; Bhattacharya, Apurba; Mathad, Vijayavitthal T.
Synthetic Communications, 2007 , vol. 37, # 19 p. 3439 - 3446
反应条件
hydrogenchloride in methanol Heating;
参考文献
Vankawala, Pravinchandra J.; Kolla, Naveenkumar; Elati, Chandrashekar R.; Sreenivasulu; Kumar, K. Arun; Anjaneyulu, Yerrimilli; Venkatraman, Sundaram; Bhattacharya, Apurba; Mathad, Vijayavitthal T.
Synthetic Communications, 2007 , vol. 37, # 19 p. 3439 - 3446
反应条件
Candida antarctica lipase B; potassium tert-butylate; sodium carbonate; RuCl(CO)2(η5-C5Ph5) in tetrahydrofuran; toluene
T=20°C; 72 h;
参考文献
Bogar, Krisztian; Baeckvall, Jan-E.
Tetrahedron Letters, 2007 , vol. 48, # 31 p. 5471 - 5474
反应条件
1: sodium borohydride
2: 5.5 g / lipase CAL-B; 2,6-lutidine / toluene / 68 h / 40 °C
View Scheme
参考文献
Vankawala, Pravinchandra J.; Kolla, Naveenkumar; Elati, Chandrashekar R.; Sreenivasulu; Kumar, K. Arun; Anjaneyulu, Yerrimilli; Venkatraman, Sundaram; Bhattacharya, Apurba; Mathad, Vijayavitthal T.
Synthetic Communications, 2007 , vol. 37, # 19 p. 3439 - 3446
反应条件
bis(norbornadiene)rhodium(I) tetrafluoroborate; C60H46O4P2; hydrogen in tetrahydrofuran
T=20°C; P=30003 Torr; 18 h; Inert atmosphereAutoclave; optical yield given as percent ee;
参考文献
Etayo, Pablo; Nunez-Rico, Jose Luis; Fernandez-Perez, Hector; Vidal-Ferran, Anton
Chemistry - A European Journal, 2011 , vol. 17, # 50 p. 13978 - 13982
反应条件
Candida antartica lipase B in various solvent(s)
T=40°C; P=67505.4 Torr; 2 h;
参考文献
Matsuda, Tomoko; Tsuji, Kazuhiko; Kamitanaka, Takashi; Harada, Tadao; Nakamura, Kaoru; Ikariya, Takao
Chemistry Letters, 2005 , vol. 34, # 8 p. 1102 - 1103
反应条件
2,6-dimethylpyridine; lipase CAL-B in toluene
T=40°C; 68 h;
参考文献
Vankawala, Pravinchandra J.; Kolla, Naveenkumar; Elati, Chandrashekar R.; Sreenivasulu; Kumar, K. Arun; Anjaneyulu, Yerrimilli; Venkatraman, Sundaram; Bhattacharya, Apurba; Mathad, Vijayavitthal T.
Synthetic Communications, 2007 , vol. 37, # 19 p. 3439 - 3446
