2-羟基-4-甲基嘧啶盐酸盐合成路线 (共 4 条)
反应条件
hydrogenchloride in ethanol 1 h;
参考文献
Lee, Thomas W. S.; Rettig, Steven J.; Stewart, Ross; Trotter, James
Canadian Journal of Chemistry, 1984 , vol. 62, p. 1194 - 1202
反应条件
1: 2-hydroxy-4-methylpyrimidine hydrochloride With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; caesium carbonate in tetrahydrofuran T=20°C; 0.833333 h; Inert atmosphere; 2: methanol With caesium carbonate T=20°C; 0.166667 h;
参考文献
Kokatla, Hari Prasad; Lakshman, Mahesh K.
Organic Letters, 2010 , vol. 12, # 20 p. 4478 - 4481
参考文献
Bulletin des Societes Chimiques Belges, , vol. 66, p. 276,289
Journal of the Chemical Society, , p. 1004,1015
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, vol. 24, p. 84
反应条件
(i) COCl2, CHCl3, (ii) /BRN= 3691454/, Et3N, (iii) NH2OH; Multistep reaction;
参考文献
Bergstrom,D.E. et al.
Journal of Organic Chemistry, 1972 , vol. 37, p. 3902 - 3905