1: With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane
24 h; Heating / reflux;
2: With potassium fluoride in 1,4-dioxane; diethyl ether; water
T=20°C; 2 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/54202 A1, 2005 ;
Location in patent: Page/Page column 37 ;
WO 2005/054202 A1