1-甲基-1H-苯并咪唑-6-羧酸合成路线 （共 4 条）
反应条件
hydrogenchloride; potassium permanganate
反应条件
1: 2-(4,6-difluoro-1H-benzoimidazol-2-ylmethyl)-3-methyl-3H-benzoimidazole-5-carboxylic acid With N-fluoro-N-(phenylsulfonyl)benzene-sulfonamide in 1,4-dioxane Heating; 2: methanol Heating;
参考文献
Dener, Jeffrey M.; O'Bryan, Colin; Yee, Robert; Shelton, Emma J.; Sperandio, David; Mahajan, Tania; Palmer, James T.; Spencer, Jeffrey R.; Tong, Zhiwei
Tetrahedron Letters, 2006 , vol. 47, # 27 p. 4591 - 4595
反应条件
1: hydrogen; palladium on activated charcoal / ethyl acetate 2: hydrogenchloride / |Reflux; |Inert atmosphere 3: potassium hydroxide; water / methanol / 3 h / 60 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 24 p. 6838 - 6841
反应条件
1: hydrogenchloride / |Reflux; |Inert atmosphere 2: potassium hydroxide; water / methanol / 3 h / 60 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 24 p. 6838 - 6841
