7-甲氧基-2-甲基-1H-吲哚合成路线 (共 13 条)
反应条件
1: acetic acid; aqueous H2SO4
2: ethyl acetate; Raney nickel / Hydrogenation
View Scheme
参考文献
Blair; Newbold
Journal of the Chemical Society, 1955 , p. 2871,2873
反应条件
Multistep reaction. Title compound not separated from byproducts;
参考文献
Macleod, Calum; McKiernan, Gordon J.; Guthrie, Emma J.; Farrugia, Louis J.; Hamprecht, Dieter W.; Macritchie, Jackie; Hartley, Richard C.
Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 387 - 401
反应条件
1: collidine / acetonitrile
2: KOH
3: NaH / dimethylformamide
4: 3 N aq. NaOH / methanol
5: SOCl2 / 1,2-dichloro-ethane
6: TEA / 1,2-dichloro-ethane
View Scheme
参考文献
Hynes Jr., John; Leftheris, Katerina; Wu, Hong; Pandit, Chennagiri; Chen, Ping; Norris, Derek J.; Chen, Bang-Chi; Zhao, Rulin; Kiener, Peter A.; Chen, Xiaorong; Turk, Lori A.; Patil-Koota, Vina; Gillooly, Kathleen M.; Shuster, David J.; McIntyre, Kim W.
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 17 p. 2399 - 2402