反应条件
1: DMAP / tetrahydrofuran / Ambient temperature
2: 1.) LiAlH4, 2.) H2, AcOH / 2) Pd/C / 1.) from 0 deg C to RT, 2.) EtOAC, EtOH
3: BBr3 / CH2Cl2 / -78 - 0 °C
4: ZnCl2 / ethanol / 110 - 120 °C
View Scheme
参考文献
Edwards, James P.; Higuchi, Robert I.; Winn, David T.; Pooley, Charlotte L. F.; Caferro, Thomas R.; Hamann, Lawrence G.; Zhi, Lin; Marschke, Keith B.; Goldman, Mark E.; Jones, Todd K.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 7 p. 1003 - 1008
