(R)-(-)-1-(9-蒽基)-2,2,2-三氟乙醇合成路线 （共 9 条）
反应条件
(-)-(S)-BINAL-H in tetrahydrofuran T=-20°C; 22 h;
参考文献
Chong, J. Michael; Mar, Eduardo K.
Journal of Organic Chemistry, 1991 , vol. 56, # 2 p. 893 - 896
参考文献
Journal of the Chemical Society, Chemical Communications, , # 3 p. 301 - 302
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 2 h;
参考文献
Tetrahedron Asymmetry, , vol. 17, # 23 p. 3237 - 3243
反应条件
potassium hydroxide in tetrahydrofuran; water 4 h;
参考文献
Tetrahedron Asymmetry, , vol. 17, # 23 p. 3237 - 3243
反应条件
potassium carbonate in tetrahydrofuran 4 h;
参考文献
Tetrahedron Asymmetry, , vol. 17, # 23 p. 3237 - 3243
反应条件
(-)-(S)-BINAL-H in tetrahydrofuran effect of temperature, effect of the amount of BINAL-H; further trifluoromethyl ketones and 9-acetylanthracene; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 56, # 2 p. 893 - 896
反应条件
1: 1) n-BuLi / 2) ether, -78 deg C to room temperature 2: 90 percent / (S)-BINAL-H / tetrahydrofuran / 22 h / -20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 2 p. 893 - 896
反应条件
1: 85 percent / EtAlCl2 / CH2Cl2; hexane / 1 h / -78 °C 2: 95 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 17, # 23 p. 3237 - 3243
反应条件
Birman's catalyst; sodium sulfate; N-ethyl-N,N-diisopropylamine in chloroform T=0°C; 1 h; Resolution of racemate; Kinetics; Reagent/catalyst; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 77, # 4 p. 1722 - 1737
