6-溴-2,2-二甲基己腈合成路线 （共 5 条）
反应条件
(i) LDA, HMPA, benzene, (ii) /BRN= 1071199/, Et2O; Multistep reaction;
参考文献
Bulletin de la Societe Chimique de France, , p. 1710 - 1714
反应条件
potassium iodide; potassium carbonate in dimethyl sulfoxide
参考文献
Bristol-Myers Squibb Pharma Company
Patent: EP1293214 A2, 2003 ;
反应条件
1: potassium tert-butoxide / tetrahydrofuran / 4 h / 20 °C 2: 7.66 g / LiAlH4 / diethyl ether / 3 h / Heating View Scheme
参考文献
Cochet, Thomas; Bellosta, Veronique; Roche, Didier; Ortholand, Jean-Yves; Greiner, Alfred; Cossy, Janine
Chemical Communications, 2012 , vol. 48, # 87 p. 10745 - 10747
反应条件
sodium t-butanolate in tetrahydrofuran
参考文献
Cochet, Thomas; Bellosta, Veronique; Roche, Didier; Ortholand, Jean-Yves; Greiner, Alfred; Cossy, Janine
Chemical Communications, 2012 , vol. 48, # 87 p. 10745 - 10747
反应条件
iodine; magnesium in N,N,N',N',N'',N''-hexamethylphosphoric triamide; diethyl ether
参考文献
Larcheveque,M. et al.
Journal of Organometallic Chemistry, 1975 , vol. 87, p. 25 - 31
