2-(1H-吲哚-3-基)-2-氧代乙胺盐酸盐合成路线 （共 5 条）
反应条件
hydrogenchloride in 1,4-dioxane
T=20°C; 4 h; Inert atmosphere;
参考文献
Sperry, Jonathan; Moody, Christopher J.
Tetrahedron, 2010 , vol. 66, # 33 p. 6483 - 6495
反应条件
1: 36 percent / pyridine / toluene / 60 °C
2: 98 percent / NaN3 / acetone; H2O / Heating
3: H2; HCl / Pd/C / methanol
View Scheme
参考文献
Jiang, Biao; Gu, Xiao-Hui
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 2 p. 363 - 371
反应条件
1: 98 percent / NaN3 / acetone; H2O / Heating
2: H2; HCl / Pd/C / methanol
View Scheme
参考文献
Jiang, Biao; Gu, Xiao-Hui
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 2 p. 363 - 371
反应条件
1: bromine / methanol / 2 h / Heating
2: acetone; CHCl3 / 3 h / 20 °C
3: conc. hydrochloric acid / ethanol / 19 h / 20 °C
View Scheme
参考文献
Iakovou; Varvaresou; Kourounakis; Stead; Sugden; Tsotinis
Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 1 p. 147 - 156
反应条件
hydrogenchloride in ethanol
Inert atmosphere;
参考文献
Miyake, Fumiko; Hashimoto, Michinao; Tonsiengsom, Sorasaree; Yakushijin, Kenichi; Horne, David A.
Tetrahedron, 2010 , vol. 66, # 26 p. 4888 - 4893
